Contraindicated (1)pentobarbital decreases amounts of vandetanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Prevent coadministration with potent CYP3A4 inducers; these medicine decrease publicity to vandetanib by up to forty%.pentobarbital will lessen the level or influence of aripiprazole by affecting hepatic/intest

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